Urate Excretion
نویسندگان
چکیده
منابع مشابه
Normal fractional urate excretion identifies hyponatremic patients with reset osmostat.
BACKGROUND Reset osmostat (RO) occurs in 36% of patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH) and is not often considered when evaluating hyponatremic patients. Patients with RO are not usually treated, but recent awareness that symptoms are associated with mild hyponatremia creates a therapeutic dilemma. We encountered patients with hyponatremia, hypouricemia a...
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The purpose of this literature study is to give an overview of nitrogen and purine metabolism in general and in particular of the molecular mechanisms for the higher uric acid excretion in Dalmatian dogs. The character portrayed by the Dalmatian breed appears to be connected whit a malfunction within purine metabolism, some studies point at a kidney disease whereas other at a liver disease. Alt...
متن کاملThe role of urinary precipitates in the excretion of electrolytes and urate in the domestic fowl.
1. In order to quantify losses of Na and K associated with precipitate fractions in semi-solid avian urines, Na, K, uric acid and urates (UA + U) and inulin were measured in plasma, in whole ureteral urine, and in urinary precipitates of hens. Ten animals were used, five fed a control commercial poultry meal (Diet A) and five maintained on a high protein, low-Na feed (Diet B). 2. In ureteral ur...
متن کاملThe Renal Mechanism for Urate Excretion in the Dalmatian Coach-hound
1. The renal mechanism for urate excretion in the Dalmatian dog resembles that in birds. Urate is cleared at a rate considerably greater than the glomerular filtration rate, indicating that its excretion is the result of both glomerular filtration and active tubular secretion. The basic physiological mechanisms involved in the anomalous purine metabolism of the Dalmatian are indicated and their...
متن کاملHyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2
To clarify the physiological and pathophysiological roles of intestinal urate excretion via ABCG2 in humans, we genotyped ABCG2 dysfunctional common variants, Q126X (rs72552713) and Q141K (rs2231142), in end-stage renal disease (hemodialysis) and acute gastroenteritis patients, respectively. ABCG2 dysfunction markedly increased serum uric acid (SUA) levels in 106 hemodialysis patients (P = 1.1 ...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1966
ISSN: 0035-9157
DOI: 10.1177/003591576605900404